Literally what happened after the Taiping Rebellion. This is the historical reason for Afghanistan and The Golden Triangle region currently being the largest opium producers in the world.
Read up on the PRC’s 1952 “Directive on Eradication of Drug Epidemic” and “mass line methodology” for how the “opium problem” was actually historically dealt with. Watching what the Taliban do over the next decade may also provide some insight.
I know you mean human brain, but the point is that the principles largely exist and the progress is accelerating.
However, one of the key learnings from the linked project is that the brain and body are intrinsically linked and biology is a nightmare mess of spaghetti code. Simulating just the brain has limited benefits and will not likely simulate a person or consciousness any more than simulating small pieces of a brain.
For some further reading: https://www.sciencedirect.com/science/article/abs/pii/S030645222100021X (scihub)
That says more about how you treat your tools and view your material surroundings than speaking to any sort of universal truth.
Saying that empathy is reserved for things you’re trying to fuck isn’t the “Gotcha!” you think it is.
Again, says more about you than anything.