A systematic review of 49 imaging studies highlights how COVID-19 affects the human brain. Researchers found widespread structural and functional changes in areas responsible for memory, emotion, and attention, providing insight into enduring neurological symptoms like brain fog.
Cystic fibrosis also shows an increase in gray matter in several areas of the brain, by a pretty considerable amount too. The hypothesis with CF is that it’s due to hypoxia, I wonder if this the same or similar phenomena.